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Achieving air pollutant emission reduction targets with minimum abatement costs: An enterprise-level

Frontiers of Environmental Science & Engineering 2022, Volume 16, Issue 2, doi: 10.1007/s11783-021-1459-6

Abstract:

• Quantification of efficiency and fairness of abatement allocation are optimized.

Keywords： Pollutant emission reduction allocation     Emission reduction measures     Total abatement cost     Economic efficiency     Abatement space    

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Cold stress responsive microRNAs and their targets in

Jingyi WANG,Juhua LIU,Caihong JIA,Hongxia MIAO,Jianbin ZHANG,Zhuo WANG,Biyu XU,Zhiqiang JIN

Frontiers of Agricultural Science and Engineering 2016, Volume 3, Issue 4,   Pages 335-345 doi: 10.15302/J-FASE-2016121

Abstract: Although miRNAs and their targets have been identified in several banana species, their participation

Keywords： cold stress     microRNA     Musa balbisiana    

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Endostatin specifically targets both tumor blood vessels and lymphatic vessels

Wei Zhuo, Yang Chen, Xiaomin Song, Yongzhang Luo

Frontiers of Medicine 2011, Volume 5, Issue 4,   Pages 336-340 doi: 10.1007/s11684-011-0163-5

Abstract: Endostatin, a 20 kDa C-terminal fragment of collagen XVIII, was first identified as a potent angiogenic inhibitor. The anti-angiogenic function of endostatin has been well documented during the past decade. Recently, several studies demonstrated that endostatin also inhibits tumor lymphangiogenesis and lymphatic metastasis. However, the exact mechanism that endostatin executes its anti-angiogenic and anti-lymphangiogenic functions remains elusive. In the current mini-review, we briefly summarize recent novel findings, including the functions of endostatin targeting not only angiogenesis but also lymphangiogenesis, and the underlying mechanism by which endostatin internalization regulates its biological functions.

Keywords： endostatin     angiogenesis     lymphangiogenesis     nystatin     internalization     tumor    

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Expanding Fleet of Autonomous Floating Robots Targets Deeper Understanding of Global Ocean Dynamics

Chris Palmer

Engineering 2023, Volume 22, Issue 3,   Pages 10-13 doi: 10.1016/j.eng.2023.01.001

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Emerging molecular subtypes and therapeutic targets in B-cell precursor acute lymphoblastic leukemia

Jianfeng Li, Yuting Dai, Liang Wu, Ming Zhang, Wen Ouyang, Jinyan Huang, Saijuan Chen

Frontiers of Medicine 2021, Volume 15, Issue 3,   Pages 347-371 doi: 10.1007/s11684-020-0821-6

Abstract: We provide an update on our knowledge of emerging molecular subtypes and therapeutic targets in BCP-ALL

Keywords： BCP-ALL     subtypes     translocation     aneuploidy     sequence mutations    

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metabolomics reveals the perturbed metabolic pathways and biomarkers of Yang Huang syndrome as potential targets

Heng Fang, Aihua Zhang, Xiaohang Zhou, Jingbo Yu, Qi Song, Xijun Wang

Frontiers of Medicine 2020, Volume 14, Issue 5,   Pages 651-663 doi: 10.1007/s11684-019-0709-5

Abstract: High-throughput metabolomics can clarify the underlying molecular mechanism of diseases via the qualitative and quantitative analysis of metabolites. This study used the established Yang Huang syndrome (YHS) mouse model to evaluate the efficacy of geniposide (GEN). Urine metabolic data were quantified by ultra-performance liquid chromatography–tandem mass spectrometry. The non-target screening of the massive biological information dataset was performed, and a total of 33 metabolites, including tyramine glucuronide, aurine, and L-cysteine, were identified relating to YHS. These differential metabolites directly participated in the disturbance of phase I reaction and hydrophilic transformation of bilirubin. Interestingly, they were completely reversed by GEN. While, as the auxiliary technical means, we also focused on the molecular prediction and docking results in network pharmacological and integrated analysis part. We used integrated analysis to communicate the multiple results of metabolomics and network pharmacology. This study is the first to report that GEN indirectly regulates the metabolite “tyramine glucuronide” through its direct effect on the target heme oxygenase 1 . Meanwhile, heme oxygenase-1, a prediction of network pharmacology, was the confirmed metabolic enzyme of phase I reaction in hepatocytes. Our study indicated that the combination of high-throughput metabolomics and network pharmacology is a robust combination for deciphering the pathogenesis of the traditional Chinese medicine (TCM) syndrome.

Keywords： metabolomics     liquid chromatography-mass spectrometry     metabolites     metabolic pathways    

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GREENHOUSE GAS AND AMMONIA EMISSION MITIGATION PRIORITIES FOR UK POLICY TARGETS

Frontiers of Agricultural Science and Engineering 2023, Volume 10, Issue 2,   Pages 268-280 doi: 10.15302/J-FASE-2023495

Abstract:

● An expert survey highlighted the most effective strategies for GHG and ammonia mitigation.

Keywords： agriculture     ammonia     greenhouse gas     mitigation     net zero    

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Detecting slowlymoving infrared targets using temporal filtering and association strategy Article

Jing-li GAO,Cheng-lin WEN,Zhe-jing BAO,Mei-qin LIU

Frontiers of Information Technology & Electronic Engineering 2016, Volume 17, Issue 11,   Pages 1176-1185 doi: 10.1631/FITEE.1601203

Abstract: The special characteristics of slowly moving infrared targets, such as containing only a few pixels,First, a temporal target detection model is developed to segment the interested targets.Then a graph matching model is presented to associate the targets obtained at different times.is performed many times to form continuous trajectories which can be used to help disambiguate targetsExperimental results show that the proposed method can detect slowly moving infrared targets in complex

Keywords： Temporal target detection     Slowly moving targets     Graph matching     Target association    

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Research on a comprehensive evaluation model on the choice of M&A targets based on principal componential

Luo Yixin

Strategic Study of CAE 2009, Volume 11, Issue 11,   Pages 92-96

Abstract: feasibility of the above-mentioned evaluation index system and the selection evaluation model,and the M&A targets

Keywords： principal componential analysis     M&A     target choice     evaluation index system     evaluation model    

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Range estimation based on symmetry polynomial aided Chinese remainder theorem for multiple targets in Research Articles

Chenghu CAO, Yongbo ZHAO,ybzhao@xidian.edu.cn

Frontiers of Information Technology & Electronic Engineering 2022, Volume 23, Issue 2,   Pages 304-316 doi: 10.1631/FITEE.2000418

Abstract: To avoid Doppler ambiguity, pulse Doppler radar may operate on a high pulse repetition frequency (PRF). The use of a high PRF can, however, lead to in many cases. At present, the major efficient solution to solve is based on a waveform design scheme. It adds complexity to a radar system. However, the traditional multiple-PRF-based scheme is difficult to be applied in because of unknown correspondence between the target range and measured range, especially using the Chinese remainder theorem (CRT) algorithm. We make a study of the CRT algorithm for when the residue set contains noise error. In this paper, we present a symmetry polynomial aided CRT algorithm to effectively achieve range estimation of when the measured ranges are overlapped with noise error. A closed-form and robust CRT algorithm for single target and the Aitken acceleration algorithm for finding roots of a polynomial equation are used to decrease the computational complexity of the proposed algorithm.

Keywords： Range ambiguity     Erroneous range     Multiple targets     Symmetry polynomial aided Chinese remainder theorem    

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A Clinical and Animal Experiment Integrated Platform for Small-Molecule Screening Reveals Potential Targets Article

Hui Xiong, Ai-Hua Zhang, Ya-Jing Guo, Xiao-Hang Zhou, Hui Sun, Le Yang, Heng Fang, Guang-Li Yan, Xi-Jun Wang

Engineering 2021, Volume 7, Issue 9,   Pages 1293-1305 doi: 10.1016/j.eng.2020.12.016

Abstract: prescription in traditional Chinese medicine (TCM) has great complexity, with multiple components and multiple targetsThis study established an innovative strategy for discovering the potential targets and active compoundsWe found that eight active components could modulate five key targets.These key targets were further verified by enzyme-linked immunosorbent assay (ELISA), which indicatedEight main effective compounds were discovered and correlated with the key targets and pathways.

Keywords： Efficacy     Bioactive compound     Small molecule     Targets     Herbal medicine     Metabolomics    

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Joint tracking and classification of extended targets with complex shapes Research Articles

Liping Wang, Ronghui Zhan, Yuan Huang, Jun Zhang, Zhaowen Zhuang,zhanrh@nudt.edu.cn

Frontiers of Information Technology & Electronic Engineering 2021, Volume 22, Issue 6,   Pages 839-861 doi: 10.1631/FITEE.2000061

Abstract: Simulations indicate that: (1) the proposed JTC-RHM method can classify the targets with complex shapes

Keywords： 扩展目标；傅里叶描述子；联合跟踪与分类；随机超曲面模型；伯努利滤波器    

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the Fc fragment of the IgG-binding protein as a serum biomarker and implicates potential therapeutic targets

Frontiers of Medicine 2022, Volume 16, Issue 3,   Pages 378-388 doi: 10.1007/s11684-021-0840-y

Abstract: Macrolide and corticosteroid resistance has been reported in patients with Mycoplasma pneumoniae (MP) pneumonia (MPP). MP clearance is difficult to achieve through antibiotic treatment in sensitive patients with severe MPP (SMPP). SMPP in children might progress to airway remodeling and even bronchiolitis/bronchitis obliterans. Therefore, identifying serum biomarkers that indicate MPP progression and exploring new targeted drugs for SMPP treatment require urgency. In this study, serum samples were collected from patients with general MPP (GMPP) and SMPP to conduct proteomics profiling. The Fc fragment of the IgG-binding protein (FCGBP) was identified as the most promising indicator of SMPP. Biological enrichment analysis indicated uncontrolled inflammation in SMPP. ELISA results proved that the FCGBP level in patients with SMPP was substantially higher than that in patients with GMPP. Furthermore, the FCGBP levels showed a decreasing trend in patients with GMPP but the opposite trend in patients with SMPP during disease progression. Connectivity map analyses identified 25 possible targeted drugs for SMPP treatment. Among them, a mechanistic target of rapamycin kinase (mTOR) inhibitor, which is a macrolide compound and a cell proliferation inhibitor, was the most promising candidate for targeting SMPP. To our knowledge, this study was the first proteomics-based characterization of patients with SMPP and GMPP.

Keywords： severe Mycoplasma pneumoniae pneumonia     children     proteomics     Fc fragment of the IgG-binding protein     mechanistic target of rapamycin kinase inhibitor    

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Decentralized Searching of Multiple Unknown and Transient Radio Sources with Paired Robots Article

Chang-Young Kim, Dezhen Song, Jingang Yi, Xinyu Wu

Engineering 2015, Volume 1, Issue 1,   Pages 58-65 doi: 10.15302/J-ENG-2015010

Abstract:

In this paper, we develop a decentralized algorithm to coordinate a group of mobile robots to search for unknown and transient radio sources. In addition to limited mobility and ranges of communication and sensing, the robot team has to deal with challenges from signal source anonymity, short transmission duration, and variable transmission power. We propose a two-step approach: First, we decentralize belief functions that robots use to track source locations using checkpoint-based synchronization, and second, we propose a decentralized planning strategy to coordinate robots to ensure the existence of checkpoints. We analyze memory usage, data amount in communication, and searching time for the proposed algorithm. We have implemented the proposed algorithm and compared it with two heuristics. The experimental results show that our algorithm successfully trades a modest amount of memory for the fastest searching time among the three methods.

Keywords： wireless localization     networked robots     transient targets    

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On Differentiation Among Pilot Signals of Multiple Mobile Targets in Retro-Reflective Beamforming for Article

Xin Wang, Long Li, Tie Jun Cui, Mingyu Lu

Engineering 2023, Volume 30, Issue 11,   Pages 55-62 doi: 10.1016/j.eng.2023.08.010

Abstract: schemes for wireless power transmission to multiple wireless power receivers (referred to herein as "targetsThe experimental results demonstrate that, when multiple targets broadcast continuous-wave pilot signalswireless power transmitter is capable of generating multiple wireless power beams aiming at the respective targetsHowever, various practical complications are identified when the pilot signals of multiple targets areis essential for a retro-reflective wireless power transmitter to explicitly discriminate multiple targets

Keywords： Wireless power transmission     Microwave antenna array     Retro-reflective beamforming     Pilot signal     Multiple access    

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Title Author Date Type Operation

Achieving air pollutant emission reduction targets with minimum abatement costs: An enterprise-level

Journal Article

Cold stress responsive microRNAs and their targets in

Jingyi WANG,Juhua LIU,Caihong JIA,Hongxia MIAO,Jianbin ZHANG,Zhuo WANG,Biyu XU,Zhiqiang JIN

Journal Article

Endostatin specifically targets both tumor blood vessels and lymphatic vessels

Wei Zhuo, Yang Chen, Xiaomin Song, Yongzhang Luo

Journal Article

Expanding Fleet of Autonomous Floating Robots Targets Deeper Understanding of Global Ocean Dynamics

Chris Palmer

Journal Article

Emerging molecular subtypes and therapeutic targets in B-cell precursor acute lymphoblastic leukemia

Jianfeng Li, Yuting Dai, Liang Wu, Ming Zhang, Wen Ouyang, Jinyan Huang, Saijuan Chen

Journal Article

metabolomics reveals the perturbed metabolic pathways and biomarkers of Yang Huang syndrome as potential targets

Heng Fang, Aihua Zhang, Xiaohang Zhou, Jingbo Yu, Qi Song, Xijun Wang

Journal Article

GREENHOUSE GAS AND AMMONIA EMISSION MITIGATION PRIORITIES FOR UK POLICY TARGETS

Journal Article

Detecting slowlymoving infrared targets using temporal filtering and association strategy

Jing-li GAO,Cheng-lin WEN,Zhe-jing BAO,Mei-qin LIU

Journal Article

Research on a comprehensive evaluation model on the choice of M&A targets based on principal componential

Luo Yixin

Journal Article

Range estimation based on symmetry polynomial aided Chinese remainder theorem for multiple targets in

Chenghu CAO, Yongbo ZHAO,ybzhao@xidian.edu.cn

Journal Article

A Clinical and Animal Experiment Integrated Platform for Small-Molecule Screening Reveals Potential Targets

Hui Xiong, Ai-Hua Zhang, Ya-Jing Guo, Xiao-Hang Zhou, Hui Sun, Le Yang, Heng Fang, Guang-Li Yan, Xi-Jun Wang

Journal Article

Joint tracking and classification of extended targets with complex shapes

Liping Wang, Ronghui Zhan, Yuan Huang, Jun Zhang, Zhaowen Zhuang,zhanrh@nudt.edu.cn

Journal Article

the Fc fragment of the IgG-binding protein as a serum biomarker and implicates potential therapeutic targets

Journal Article

Decentralized Searching of Multiple Unknown and Transient Radio Sources with Paired Robots

Chang-Young Kim, Dezhen Song, Jingang Yi, Xinyu Wu

Journal Article

On Differentiation Among Pilot Signals of Multiple Mobile Targets in Retro-Reflective Beamforming for

Xin Wang, Long Li, Tie Jun Cui, Mingyu Lu

Journal Article